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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA2
All Species:
16.97
Human Site:
S394
Identified Species:
31.11
UniProt:
P54646
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54646
NP_006243.2
552
62320
S394
L
N
T
T
K
P
K
S
L
A
V
K
K
A
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086410
550
62775
H390
L
N
P
Q
K
S
K
H
Q
G
V
R
K
A
K
Dog
Lupus familis
XP_546691
722
81319
S564
L
N
T
T
K
P
K
S
L
A
V
K
K
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRK8
552
61988
S394
L
N
T
T
K
P
K
S
L
A
V
K
K
A
K
Rat
Rattus norvegicus
Q09137
552
62239
S394
L
N
T
T
K
P
K
S
L
A
V
K
K
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
H359
L
N
P
Q
K
S
K
H
Q
G
V
R
R
A
K
Chicken
Gallus gallus
Q9IA88
798
88848
T580
R
A
S
D
T
S
L
T
Q
G
L
K
A
F
R
Frog
Xenopus laevis
NP_001088426
560
64038
Q400
N
P
Q
K
S
K
H
Q
V
G
V
R
R
A
K
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
T519
Q
S
L
L
Q
P
P
T
L
Q
L
L
N
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
V357
V
A
S
S
P
P
P
V
A
F
S
P
N
D
T
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
A457
D
N
T
E
A
S
G
A
N
R
N
K
R
A
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
R378
E
T
M
E
G
T
P
R
M
H
P
A
E
S
V
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
H452
I
T
Q
Q
R
T
Y
H
Q
S
P
F
M
D
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
76.4
73.8
N.A.
97.6
98.1
N.A.
71.1
27.3
75.3
22.3
N.A.
N.A.
66.1
53.6
N.A.
Protein Similarity:
100
N.A.
86.7
75.2
N.A.
98.5
99
N.A.
81.1
42.6
85
32.6
N.A.
N.A.
77.7
65.6
N.A.
P-Site Identity:
100
N.A.
53.3
100
N.A.
100
100
N.A.
46.6
6.6
20
13.3
N.A.
N.A.
6.6
33.3
N.A.
P-Site Similarity:
100
N.A.
60
100
N.A.
100
100
N.A.
60
33.3
40
40
N.A.
N.A.
26.6
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.9
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.3
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
8
0
0
8
8
31
0
8
8
62
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
0
0
0
0
0
16
0
% D
% Glu:
8
0
0
16
0
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
8
0
8
0
% F
% Gly:
0
0
0
0
8
0
8
0
0
31
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
8
24
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
47
8
47
0
0
0
0
47
39
0
62
% K
% Leu:
47
0
8
8
0
0
8
0
39
0
16
8
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
8
0
0
0
8
0
8
% M
% Asn:
8
54
0
0
0
0
0
0
8
0
8
0
16
0
0
% N
% Pro:
0
8
16
0
8
47
24
0
0
0
16
8
0
0
0
% P
% Gln:
8
0
16
24
8
0
0
8
31
8
0
0
0
0
8
% Q
% Arg:
8
0
0
0
8
0
0
8
0
8
0
24
24
0
8
% R
% Ser:
0
8
16
8
8
31
0
31
0
8
8
0
0
8
0
% S
% Thr:
0
16
39
31
8
16
0
16
0
0
0
0
0
0
8
% T
% Val:
8
0
0
0
0
0
0
8
8
0
54
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _